Department of Microbiome and Applied Bioinformatics

Department of Microbiome and Applied Bioinformatics

©IngridHilbert

Research

  • Structure and composition of the stomach microbiota in the functional context of the gastrointestinal tract
  • Dysbiosis, diarrhea and inflammation: intrinsic microbiota organization and human-microbiome interactions
  • Personalized nutrition: association with taxonomic, metabolic and functional microbiome parameters
  • Microbiome transplantation: establishment, stability and therapeutic modulation of the microbiome

Methods

  • Microbial genomics and bioinformatic sequence analysis
  • Quantitative taxonomic and functional  microbiota characterization
  • DNA/RNA-based high-throughput sequencing
  • Strain-level metagenomic microbiota analysis

Our group uses microbial genomics and other high-throughput methods in association with new bioinformatic tools to study the microbiome. We focus on the identification and characterization of those factors that are responsible for shaping the composition and function of the microbiome. Our goal is to improve our understanding of function and to develop new therapeutic strategies to treat microbiome-associated diseases and disorders.

Department of Microbiome and Applied Bioinformatics (140d)

Garbenstraße 30
Bio1.U2
70599 Stuttgart

Postal address:
University of Hohenheim
Department of Microbiome and Applied Bioinformatics (140d)
70593 Stuttgart
Germany

+49 (0)711 459 24840
Email

Research Projects (Selection)

Stomach Microbiome
The stomach function in the context of gastric and intestinal dysbiosis and after bariatric surgery – collaboration with the Medical University Graz (Austria) and the Sana Hospital Stuttgart

Neonatal Microbiome
Impact of birth and microbial transfer on neonatal microbiome establishment, development and function – DFG-funded collaboration with the Olgahospital Stuttgart

Microbiome Transplantation
Mechanisms and functions of fecal microbiota transplantation (FMT) and basics of microbiome stability, transfer and modulation – collaboration with the Sinai Hospital Baltimore (USA) and the Medical University Graz (Austria)

Microbial Strain Analysis
Development of bioinformatic tools for the identification and comparative analysis of microbial strains in metagenomic sequence data

Team

Andrade Binder, Nilza
Secretary

Fricke, W. Florian, Prof. Dr.

Director
Lendl, SimoneSecretary
Ruple, Hannah
PhD student
Schmidt, NinaPhD student
Schumacher, Monika
Laboratory Management
Fritz, CarolinPhD student
Döbereiner, LisaM.Sc.
Maier, CarinaM.Sc.
Schintgen, LynnPhD student

Teaching

Our group teaches topics related to microbiome research, nutrigenomics, personalized medicine / nutrition, and applied bioinformatics in the Bachelor and Master of Science programs of Nutritional Sciences at the University of Hohenheim.

In the BSc program our main teaching focus is on the basics of molecular biology and the concepts, methods and applications of nutrigenomics and microbiome research. In the MSc program we expand on the theoretical background of nutrigenomics and microbiome research by providing practical introductions to experimental lab work and bioinformatics analyses.

Find our courses in the course catalog via HohCampus. Follow the folder structure: Fakultät Naturwissenschaften > Ernährungswissenschaften (140) > Fg. Mikrobiom und Angewandte Bioinformatik (140d)

Publications & Profile